Interrogation of gossypol therapy in glioblastoma implementing cell line and patient-derived tumour models

BACKGROUND: Glioblastoma (GBM), being a highly vascularised and locally invasive tumour, is an attractive target for anti-angiogenic and anti-invasive therapies. The GBM/endothelial cell response to gossypol/temozolomide (TMZ) treatment was investigated with a particular aim to assess treatment effe...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Jarzabek, M A, Amberger-Murphy, V, Callanan, J J, Gao, C, Zagozdzon, A M, Shiels, L, Wang, J, Ligon, K L, Rich, B E, Dicker, P, Gallagher, W M, Prehn, J H M, Byrne, A T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264441/
https://ncbi.nlm.nih.gov/pubmed/25375271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.529
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