Combination of specific single chain antibody variable fragment and siRNA has a synergistic inhibitory effect on the propagation of avian influenza virus H5N1 in chicken cells

BACKGROUND: The avian influenza virus (AIV) causes frequent disease with high morbidity and mortality. RNA interference (RNAi) has been shown to provide an effective antiviral defense in animals, and several studies have focused on harnessing small interfering RNAs (siRNAs) to inhibit viral infectio...

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Detalhes bibliográficos
Publicado no:Virol J
Main Authors: Wang, Shuang, Zhang, Peng, He, Fei, Wang, Ji-Gui, Sun, Jia-Zeng, Li, Zhi-Li, Yi, Bao, Xi, Ji, Mao, Ya-Ping, Hou, Qiang, Yuan, Dao-Li, Zhang, Zi-Ding, Liu, Wei-Quan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264339/
https://ncbi.nlm.nih.gov/pubmed/25471220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-014-0208-x
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