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Cerebrotendinous xanthomatosis: a comprehensive review of pathogenesis, clinical manifestations, diagnosis, and management

Cerebrotendinous xanthomatosis (CTX) OMIM#213700 is a rare autosomal-recessive lipid storage disease caused by mutations in the CYP27A1 gene; this gene codes for the mitochondrial enzyme sterol 27-hydroxylase, which is involved in bile acid synthesis. The CYP27A1 gene is located on chromosome 2q33-q...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Orphanet J Rare Dis
Päätekijät: Nie, Shuke, Chen, Guiqin, Cao, Xuebing, Zhang, Yunjian
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264335/
https://ncbi.nlm.nih.gov/pubmed/25424010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13023-014-0179-4
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