Thiopurine methyltransferase polymorphisms in children with acute lymphoblastic leukemia

INTRODUCTION: Acute lymphoblastic leukemia (ALL) is the most common malignancy in children. 6-mercaptopurine (6-MP) and methotrexate are backbone drugs for maintenance phase of treatment. Purine Analogs 6-MP/6-thioguanine/azathiopurine are metabolized to its inactive form by the enzyme thiopurine me...

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Bibliografiske detaljer
Udgivet i:Indian J Med Paediatr Oncol
Main Authors: Linga, Vijay Gandhi, Patchva, Dorra Babu, Mallavarapu, Krishna Mohan, Tulasi, Venkata, Kalpathi, Krishnamani Iyer, Pillai, Ashok, Gundeti, Sadashivudu, Rajappa, Senthil J, Digumarti, Raghunadharao
Format: Artigo
Sprog:Inglês
Udgivet: Medknow Publications & Media Pvt Ltd 2014
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264274/
https://ncbi.nlm.nih.gov/pubmed/25538405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0971-5851.144989
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