Sox2-Mediated Conversion of NG2 Glia into Induced Neurons in the Injured Adult Cerebral Cortex

The adult cerebral cortex lacks the capacity to replace degenerated neurons following traumatic injury. Conversion of nonneuronal cells into induced neurons has been proposed as an innovative strategy toward brain repair. Here, we show that retrovirus-mediated expression of the transcription factors...

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Bibliographic Details
Published in:Stem Cell Reports
Main Authors: Heinrich, Christophe, Bergami, Matteo, Gascón, Sergio, Lepier, Alexandra, Viganò, Francesca, Dimou, Leda, Sutor, Bernd, Berninger, Benedikt, Götz, Magdalena
Format: Artigo
Language:Inglês
Published: Elsevier 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264057/
https://ncbi.nlm.nih.gov/pubmed/25458895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.10.007
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