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A miR-590/Acvr2a/Rad51b Axis Regulates DNA Damage Repair during mESC Proliferation

Embryonic stem cells (ESCs) enable rapid proliferation that also causes DNA damage. To maintain genomic stabilization during rapid proliferation, ESCs must have an efficient system to repress genotoxic stress. Here, we show that withdrawal of leukemia inhibitory factor (LIF), which maintains the sel...

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Dades bibliogràfiques
Publicat a:Stem Cell Reports
Autors principals: Liu, Qidong, Wang, Guiying, Chen, Yafang, Li, Guoping, Yang, Dandan, Kang, Jiuhong
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264031/
https://ncbi.nlm.nih.gov/pubmed/25458897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.10.006
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