Platelet-derived growth factor triggers translocation of the insulin-regulatable glucose transporter (type 4) predominantly through phosphatidylinositol 3-kinase binding sites on the receptor.

Insulin is the only known hormone which rapidly stimulates glucose uptake in target tissues, mainly by translocation to the cell surface of the intracellular insulin-regulatable glucose transporter (glucose transporter type 4, GLUT4). We have developed a cell line for direct, sensitive detection of...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Kamohara, S, Hayashi, H, Todaka, M, Kanai, F, Ishii, K, Imanaka, T, Escobedo, J A, Williams, L T, Ebina, Y
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42640/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7862637/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.4.1077
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