SCCRO3 (DCUN1D3) Antagonizes the Neddylation and Oncogenic Activity of SCCRO (DCUN1D1)

The activity of cullin-RING type ubiquitination E3 ligases is regulated by neddylation, a process analogous to ubiquitination that culminates in covalent attachment of the ubiquitin-like protein Nedd8 to cullins. As a component of the E3 for neddylation, SCCRO/DCUN1D1 plays a key regulatory role in...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Huang, Guochang, Stock, Cameron, Bommeljé, Claire C., Weeda, Víola B., Shah, Kushyup, Bains, Sarina, Buss, Elizabeth, Shaha, Manish, Rechler, Willi, Ramanathan, Suresh Y., Singh, Bhuvanesh
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263876/
https://ncbi.nlm.nih.gov/pubmed/25349211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.585505
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