IL-28B is a Key Regulator of B- and T-Cell Vaccine Responses against Influenza

Influenza is a major cause of morbidity and mortality in immunosuppressed persons, and vaccination often confers insufficient protection. IL-28B, a member of the interferon (IFN)-λ family, has variable expression due to single nucleotide polymorphisms (SNPs). While type-I IFNs are well known to modu...

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Vydáno v:PLoS Pathog
Hlavní autoři: Egli, Adrian, Santer, Deanna M., O'Shea, Daire, Barakat, Khaled, Syedbasha, Mohammedyaseen, Vollmer, Madeleine, Baluch, Aliyah, Bhat, Rakesh, Groenendyk, Jody, Joyce, Michael A., Lisboa, Luiz F., Thomas, Brad S., Battegay, Manuel, Khanna, Nina, Mueller, Thomas, Tyrrell, D. Lorne J., Houghton, Michael, Humar, Atul, Kumar, Deepali
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263767/
https://ncbi.nlm.nih.gov/pubmed/25503988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004556
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