Amphipathic α-Helices in Apolipoproteins Are Crucial to the Formation of Infectious Hepatitis C Virus Particles

Apolipoprotein B (ApoB) and ApoE have been shown to participate in the particle formation and the tissue tropism of hepatitis C virus (HCV), but their precise roles remain uncertain. Here we show that amphipathic α-helices in the apolipoproteins participate in the HCV particle formation by using zin...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Main Authors: Fukuhara, Takasuke, Wada, Masami, Nakamura, Shota, Ono, Chikako, Shiokawa, Mai, Yamamoto, Satomi, Motomura, Takashi, Okamoto, Toru, Okuzaki, Daisuke, Yamamoto, Masahiro, Saito, Izumu, Wakita, Takaji, Koike, Kazuhiko, Matsuura, Yoshiharu
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263759/
https://ncbi.nlm.nih.gov/pubmed/25502789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004534
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