Neuromuscular synapse integrity requires linkage of acetylcholine receptors to postsynaptic intermediate filament networks via rapsyn–plectin 1f complexes

Mutations in the cytolinker protein plectin lead to grossly distorted morphology of neuromuscular junctions (NMJs) in patients suffering from epidermolysis bullosa simplex (EBS)-muscular dystrophy (MS) with myasthenic syndrome (MyS). Here we investigated whether plectin contributes to the structural...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Mihailovska, Eva, Raith, Marianne, Valencia, Rocio G., Fischer, Irmgard, Banchaabouchi, Mumna Al, Herbst, Ruth, Wiche, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263455/
https://ncbi.nlm.nih.gov/pubmed/25318670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-06-1174
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