Optimized Whole-Genome Amplification Strategy for Extremely AT-Biased Template

Pathogen genome sequencing directly from clinical samples is quickly gaining importance in genetic and medical research studies. However, low DNA yield from blood-borne pathogens is often a limiting factor. The problem worsens in extremely base-biased genomes such as the AT-rich Plasmodium falciparu...

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Vydáno v:DNA Res
Hlavní autoři: Oyola, Samuel O., Manske, Magnus, Campino, Susana, Claessens, Antoine, Hamilton, William L., Kekre, Mihir, Drury, Eleanor, Mead, Daniel, Gu, Yong, Miles, Alistair, MacInnis, Bronwyn, Newbold, Chris, Berriman, Matthew, Kwiatkowski, Dominic P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
Full Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263299/
https://ncbi.nlm.nih.gov/pubmed/25240466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/dnares/dsu028
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