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Treatment selections using risk–benefit profiles based on data from comparative randomized clinical trials with multiple endpoints

In a typical randomized clinical study to compare a new treatment with a control, oftentimes each study subject may experience any of several distinct outcomes during the study period, which collectively define the “risk–benefit” profile. To assess the effect of treatment, it is desirable to utilize...

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Vydáno v:Biostatistics
Hlavní autoři: Claggett, Brian, Tian, Lu, Castagno, Davide, Wei, Lee-Jen
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263228/
https://ncbi.nlm.nih.gov/pubmed/25122189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxu037
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