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A robust association test for detecting genetic variants with heterogeneous effects

One common strategy for detecting disease-associated genetic markers is to compare the genotype distributions between cases and controls, where cases have been diagnosed as having the disease condition. In a study of a complex disease with a heterogeneous etiology, the sampled case group most likely...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biostatistics
Hauptverfasser: Yu, Kai, Zhang, Han, Wheeler, William, Horne, Hisani N., Chen, Jinbo, Figueroa, Jonine D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263227/
https://ncbi.nlm.nih.gov/pubmed/25057183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxu036
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