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Experimental study on the regulation of erlotinib-induced radiosensitization with an anti-c-MET monoclonal antibody

PURPOSE: Erlotinib is a novel therapeutic agent for cancer treatment. This study was performed to investigate the role of c-MET-PI3K-AKT pathway in the regulation of erlotinib-induced radiosensitization. METHODS: A973 lung adenocarcinoma cells treated with 6 Gy of radiation were incubated in the pre...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Zhuang, Hong-Qing, Zhuang, Hongxia, Bo, Qifu, Guo, Yihang, Wang, Jun, Zhao, Lu-Jun, Yuan, Zhi-Yong, Wang, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263203/
https://ncbi.nlm.nih.gov/pubmed/25505849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-014-0109-5
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