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Activation of c-Src tyrosine kinase mediated the degradation of occludin in ventilator-induced lung injury

BACKGROUND: Ventilator-induced lung injury (VILI) is characterized by increased alveolar permeability, pulmonary edema. The tyrosine kinase, c-Src, is involved in VILI but its role has not been fully elucidated. This study examined the relationship between c-Src activation and occludin levels in VIL...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Zhao, Tao, Liu, Mengjie, Gu, Changping, Wang, Xin, Wang, Yuelan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262993/
https://ncbi.nlm.nih.gov/pubmed/25471013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-014-0158-2
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