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Evolutionary Importance of the Intramolecular Pathways of Hydrolysis of Phosphate Ester Mixed Anhydrides with Amino Acids and Peptides

Aminoacyl adenylates (aa-AMPs) constitute essential intermediates of protein biosynthesis. Their polymerization in aqueous solution has often been claimed as a potential route to abiotic peptides in spite of a highly efficient CO(2)-promoted pathway of hydrolysis. Here we investigate the efficiency...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Liu, Ziwei, Beaufils, Damien, Rossi, Jean-Christophe, Pascal, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262824/
https://ncbi.nlm.nih.gov/pubmed/25501391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07440
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