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A load driver device for engineering modularity in biological networks

The behavior of gene modules in complex synthetic circuits is often unpredictable(1–4). Upon joining modules to create a circuit, downstream elements (such as binding sites for a regulatory protein) apply a load to upstream modules that can negatively affect circuit function(1,5). Here we devise a g...

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書目詳細資料
發表在:Nat Biotechnol
Main Authors: Mishra, Deepak, Rivera-Ortiz, Phillip M., Lin, Allen, Vecchio, Domitilla Del, Weiss, Ron
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262674/
https://ncbi.nlm.nih.gov/pubmed/25419739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3044
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