Single cell monitoring of growth arrest and morphological changes induced by transfer of wild-type p53 alleles to glioblastoma cells.

Mutation of the p53 tumor suppressor gene is one of the earliest identified genetic lesions during malignant progression of human astrocytomas. To assess the functional significance of these mutations, wild-type (WT) p53 genes were introduced into glioblastoma cell lines having mutant, WT, or null e...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Van Meir, E G, Roemer, K, Diserens, A C, Kikuchi, T, Rempel, S A, Haas, M, Huang, H J, Friedmann, T, de Tribolet, N, Cavenee, W K
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1995
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42626/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7862624/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.4.1008
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