Mallory-Denk Body (MDB) Formation Modulates Ufmylation Expression Epigenetically in Alcoholic Hepatitis (AH) and Non Alcoholic Steatohepatitis (NASH)

Promoter CpG island hypermethylation is an important mechanism for inactivating key cellular enzymes that mediate epigenetic processes in hepatitis-related hepatocellular carcinoma (HCC). The ubiquitin-fold modifiers 1 (Ufm1) conjugation pathway (Ufmylation) plays an essential role in protein degrad...

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Udgivet i:Exp Mol Pathol
Main Authors: Liu, Hui, Gong, Ming, French, Barbara A., Li, Jun, Tillman, Brittany, French, Samuel W.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262563/
https://ncbi.nlm.nih.gov/pubmed/25290169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2014.10.001
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