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Osteopontin Expression in Acute Immune Response Mediates Hippocampal Synaptogenesis and Adaptive Outcome Following Cortical Brain Injury

Traumatic brain injury (TBI) produces axotomy, deafferentation and reactive synaptogenesis. Inflammation influences synaptic repair, and the novel brain cytokine osteopontin (OPN) has potential to support axon regeneration through exposure of its integrin receptor binding sites. This study explored...

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Detalhes bibliográficos
Publicado no:Exp Neurol
Main Authors: Chan, Julie L., Reeves, Thomas M., Phillips, Linda L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262258/
https://ncbi.nlm.nih.gov/pubmed/25151457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2014.08.015
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