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A modular switch for spatial Ca(2+) selectivity in the calmodulin regulation of CaV channels

Ca(2+)/calmodulin-dependent regulation of voltage-gated Ca(V)1-2 Ca(2+) channels exhibits extraordinary modes of spatial Ca(2+) decoding and channel modulation(1–6), vital for many biological functions(6–9). A single calmodulin (CaM) constitutively associates with the channel carboxy tail(3,10–13),...

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Publicat a:Nature
Autors principals: Dick, Ivy E., Tadross, Michael R., Liang, Haoya, Tay, Lai Hock, Yang, Wanjun, Yue, David T.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262256/
https://ncbi.nlm.nih.gov/pubmed/18235447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06529
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