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A Needleless Liquid Jet Injection Delivery Method for Cardiac Gene Therapy: A Comparative Evaluation Versus Standard Routes of Delivery Reveals Enhanced Therapeutic Retention and Cardiac Specific Gene Expression

BACKGROUND: This study evaluates needleless liquid jet method and compares it with three common experimental methods: (1) Intramuscular injection (IM) (2) Left ventricular intracavitary infusion (LVIC) (3) LV intracavitary infusion with aortic and pulmonary occlusion (LVIC-OCCL). METHODS AND RESULTS...

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Bibliografske podrobnosti
izdano v:J Cardiovasc Transl Res
Main Authors: Fargnoli, AS, Katz, MG, Williams, RD, Margulies, KB, Bridges, CR
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261917/
https://ncbi.nlm.nih.gov/pubmed/25315468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12265-014-9593-1
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