Altering endoplasmic reticulum stress in a model of blast-induced traumatic brain injury controls cellular fate and ameliorates neuropsychiatric symptoms

Neuronal injury following blast-induced traumatic brain injury (bTBI) increases the risk for neuropsychiatric disorders, yet the pathophysiology remains poorly understood. Blood-brain-barrier (BBB) disruption, endoplasmic reticulum (ER) stress, and apoptosis have all been implicated in bTBI. Microve...

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Udgivet i:Front Cell Neurosci
Main Authors: Logsdon, Aric Flint, Turner, Ryan Coddington, Lucke-Wold, Brandon Peter, Robson, Matthew James, Naser, Zachary James, Smith, Kelly Elizabeth, Matsumoto, Rae Reiko, Huber, Jason Delwyn, Rosen, Charles Lee
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2014
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261829/
https://ncbi.nlm.nih.gov/pubmed/25540611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00421
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