Deficient hippocampal insulin signaling and augmented Tau phosphorylation is related to obesity- and age-induced peripheral insulin resistance: a study in Zucker rats

BACKGROUND: Insulin signaling and Tau protein phosphorylation in the hippocampi of young and old obese Zucker fa/fa rats and their lean controls were assessed to determine whether obesity-induced peripheral insulin resistance and aging are risk factors for central insulin resistance and whether cent...

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Veröffentlicht in:BMC Neurosci
Hauptverfasser: Špolcová, Andrea, Mikulášková, Barbora, Kršková, Katarína, Gajdošechová, Lucia, Zórad, Štefan, Olszanecki, Rafał, Suski, Maciej, Bujak-Giżycka, Beata, Železná, Blanka, Maletínská, Lenka
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261609/
https://ncbi.nlm.nih.gov/pubmed/25257559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-15-111
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