Increase of nerve growth factor levels in the human herniated intervertebral disc: can annular rupture trigger discogenic back pain?

INTRODUCTION: Nerve growth factor (NGF) has an important role in the generation of discogenic pain. We hypothesized that annular rupture is a trigger for discogenic pain through the action of NGF. In this study, the protein levels of NGF in discs from patients with disc herniation were examined and...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Aoki, Yasuchika, Nakajima, Arata, Ohtori, Seiji, Takahashi, Hiroshi, Watanabe, Fusako, Sonobe, Masato, Terajima, Fumiaki, Saito, Masahiko, Takahashi, Kazuhisa, Toyone, Tomoaki, Watanabe, Atsuya, Nakajima, Takayuki, Takazawa, Makoto, Nakagawa, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261264/
https://ncbi.nlm.nih.gov/pubmed/25069717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4674
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