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Label-free and real-time imaging of dehydration-induced DNA conformational changes in cellular nucleus using second harmonic microscopy

Dehydration-induced DNA conformational changes have been probed for the first time with the use of second harmonic microscopy. Unlike conventional approaches, second harmonic microscopy provides a label-free and real-time approach to detect DNA conformational changes. Upon dehydration, cellular DNA...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Zhuo, Shuangmu, Ni, Ming
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261177/
https://ncbi.nlm.nih.gov/pubmed/25491759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07416
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