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Microtubules Regulate Focal Adhesion Dynamics through MAP4K4

Disassembly of focal adhesions (FAs) allows cell retraction and integrin detachment from the ECM, processes critical for cell movement. Growth of MT (microtubule) can promote FA turnover by serving as tracks to deliver proteins essential for FA disassembly. The molecular nature of this FA “disassemb...

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Detalles Bibliográficos
Publicado en:Dev Cell
Main Authors: Yue, Jiping, Xie, Min, Gou, Xuewen, Lee, Philbert, Schneider, Michael D, Wu, Xiaoyang
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261153/
https://ncbi.nlm.nih.gov/pubmed/25490267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.10.025
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