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Altered Gene Expression Patterns During the Initiation and Promotion Stages of Neonatally Diethylstilbestrol-Induced Hyperplasia/Dysplasia/Neoplasia in the Hamster Uterus

Neonatal treatment of hamsters with diethylstilbestrol (DES) induces uterine hyperplasia/dysplasia/neoplasia (endometrial adenocarcinoma) in adult animals. We subsequently determined that the neonatal DES exposure event directly and permanently disrupts the developing hamster uterus (initiation stag...

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Detalhes bibliográficos
Publicado no:Reprod Toxicol
Main Authors: Hendry, William J., Hariri, Hussam Y., Alwis, Imala D., Gunewardena, Sumedha S., Hendry, Isabel R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261067/
https://ncbi.nlm.nih.gov/pubmed/25242112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2014.09.002
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