Results of a pilot multi-center genotype-based randomized placebo-controlled trial of propranolol to reduce pain after major thermal burn injury

BACKGROUND: Results of previous studies suggest that β-adrenoreceptor activation may augment pain, and that β-adrenoreceptor antagonists may be effective in reducing pain, particularly in individuals not homozygous for the catechol-O-methyltransferase (COMT) high activity haplotype. METHODS: Consent...

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Publicat a:Clin J Pain
Autors principals: Orrey, Danielle C, Halawa, Omar I, Bortsov, Andrey V, Shupp, Jeffrey W, Jones, Samuel W, Haith, Linwood R, Hoskins, Janelle M, Jordan, Marion H, Bangdiwala, Shrikant I, Roane, Brandon, Platts-Mills, Timothy F, Holmes, James H, Hwang, James, Cairns, Bruce A, McLean, Samuel A
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260989/
https://ncbi.nlm.nih.gov/pubmed/25084070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/AJP.0000000000000086
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