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Linear Free Energy Relationships Reveal Structural Changes in Hydrogen-Bonded Host–Guest Interactions

[Image: see text] Hydrogen bond strength in host–guest systems is modulated by many factors including preorganization, steric effects, and electronic effects. To investigate how electronic effects impact barbiturate binding in bifurcated Hamilton receptors, a library of receptors with differing elec...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: McGrath, Jacqueline M., Pluth, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260963/
https://ncbi.nlm.nih.gov/pubmed/25412431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo502325w
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