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Synthesis of Bicyclic Guanidines via Cascade Hydroamination/Michael Additions of Mono-N-acryloylpropargylguanidines
[Image: see text] A cascade silver(I)-catalyzed hydroamination/Michael addition sequence has been developed to deliver highly substituted bicyclic guanidines. This transformation gives rise to geometrically and constitutionally stable ene–guanidines and generates a remote stereocenter with moderate...
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Publicado no: | Org Lett |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American
Chemical Society
2014
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4260634/ https://ncbi.nlm.nih.gov/pubmed/25393831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol502691w |
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