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Circular permutation of a synthetic eukaryotic chromosome with the telomerator

Chromosome engineering is a major focus in the fields of systems biology, genetics, synthetic biology, and the functional analysis of genomes. Here, we describe the “telomerator,” a new synthetic biology device for use in Saccharomyces cerevisiae. The telomerator is designed to inducibly convert cir...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Mitchell, Leslie A., Boeke, Jef D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260612/
https://ncbi.nlm.nih.gov/pubmed/25378705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1414399111
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