Relating influenza virus membrane fusion kinetics to stoichiometry of neutralizing antibodies at the single-particle level

The ability of antibodies binding the influenza hemagglutinin (HA) protein to neutralize viral infectivity is of key importance in the design of next-generation vaccines and for prophylactic and therapeutic use. The two antibodies CR6261 and CR8020 have recently been shown to efficiently neutralize...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Otterstrom, Jason J., Brandenburg, Boerries, Koldijk, Martin H., Juraszek, Jarek, Tang, Chan, Mashaghi, Samaneh, Kwaks, Ted, Goudsmit, Jaap, Vogels, Ronald, Friesen, Robert H. E., van Oijen, Antoine M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260548/
https://ncbi.nlm.nih.gov/pubmed/25404330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1411755111
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