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Locus heterogeneity disease genes encode proteins with high interconnectivity in the human protein interaction network

Mutations in genes potentially lead to a number of genetic diseases with differing severity. These disease genes have been the focus of research in recent years showing that the disease gene population as a whole is not homogeneous, and can be categorized according to their interactions. Locus heter...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Keith, Benjamin P., Robertson, David L., Hentges, Kathryn E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260505/
https://ncbi.nlm.nih.gov/pubmed/25538735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00434
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