The large conductance Ca(2+) -activated K(+) (BKCa) channel regulates cell proliferation in SH-SY5Y neuroblastoma cells by activating the staurosporine-sensitive protein kinases

Here we investigated on the role of the calcium activated K(+)-channels(BKCa) on the regulation of the neuronal viability. Recordings of the K(+)-channel current were performed using patch-clamp technique in human neuroblastoma cells (SH-SY5Y) in parallel with measurements of the cell viability in t...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Curci, Angela, Mele, Antonietta, Camerino, Giulia Maria, Dinardo, Maria Maddalena, Tricarico, Domenico
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260485/
https://ncbi.nlm.nih.gov/pubmed/25538629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00476
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