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Immunophilin FK506 binding protein associated with inositol 1,4,5-trisphosphate receptor modulates calcium flux.

The immunophilin FK506 binding protein 12 (FKBP12) is associated with and modulates the ryanodine receptor calcium release channel of skeletal muscle. Ryanodine receptor has amino acid homology and functional similarity with another intracellular Ca2+ release channel, the inositol 1,4,5-trisphosphat...

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Bibliographic Details
Main Authors: Cameron, A M, Steiner, J P, Sabatini, D M, Kaplin, A I, Walensky, L D, Snyder, S H
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC42604/
https://ncbi.nlm.nih.gov/pubmed/7533300
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