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Nonsense-Mediated Decay in Genetic Disease: Friend or Foe?
Eukaryotic cells utilize various RNA quality control mechanisms to ensure high fidelity of gene expression, thus protecting against the accumulation of nonfunctional RNA and the subsequent production of abnormal peptides. Messenger RNAs (mRNAs) are largely responsible for protein production, and mRN...
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| Publicado no: | Mutat Res Rev Mutat Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4260155/ https://ncbi.nlm.nih.gov/pubmed/25485595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrrev.2014.05.001 |
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