Deletion of α-neurexin II results in autism-related behaviors in mice

Autism is a common and frequently disabling neurodevelopmental disorder with a strong genetic basis. Human genetic studies have discovered mutations disrupting exons of the NRXN2 gene, which encodes the synaptic adhesion protein α-neurexin II (Nrxn2α), in two unrelated individuals with autism, but a...

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Опубликовано в: :Transl Psychiatry
Главные авторы: Dachtler, J, Glasper, J, Cohen, R N, Ivorra, J L, Swiffen, D J, Jackson, A J, Harte, M K, Rodgers, R J, Clapcote, S J
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2014
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259993/
https://ncbi.nlm.nih.gov/pubmed/25423136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2014.123
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