Role of membrane cholesterol in spontaneous exocytosis at frog neuromuscular synapses: reactive oxygen species–calcium interplay

Using electrophysiological and optical techniques, we studied the mechanisms by which cholesterol depletion stimulates spontaneous transmitter release by exocytosis at the frog neuromuscular junction. We found that methyl-β-cyclodextrin (MCD, 10 mm)-mediated exhaustion of cholesterol resulted in the...

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Detaylı Bibliyografya
Yayımlandı:J Physiol
Asıl Yazarlar: Petrov, Alexey M, Yakovleva, Anastasiya A, Zefirov, Andrey L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BlackWell Publishing Ltd 2014
Konular:
Neuroscience: Cellular/Molecular
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259539/
https://ncbi.nlm.nih.gov/pubmed/25326454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.279695
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