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Translocation of the Escherichia coli transcription complex observed in the registers 11 to 20: "jumping" of RNA polymerase and asymmetric expansion and contraction of the "transcription bubble".

Translocation of DNA-dependent RNA polymerase along the DNA template during RNA synthesis encompasses continuous as well as discontinuous steps. This is demonstrated by chemical probing of transcription complexes stalled in consecutive registers of RNA synthesis at base positions +11, +12, +14, +16,...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Zaychikov, E, Denissova, L, Heumann, H
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1995
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42595/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7878051/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.5.1739
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