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Pharmacological PPARα Activation Markedly Alters Plasma Turnover of the Amino Acids Glycine, Serine and Arginine in the Rat

The current study extends previously reported PPARα agonist WY 14,643 (30 µmol/kg/day for 4 weeks) effects on circulating amino acid concentrations in rats fed a 48% saturated fat diet. Steady-state tracer experiments were used to examine in vivo kinetic mechanisms underlying altered plasma serine,...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ericsson, Anette, Turner, Nigel, Hansson, Göran I., Wallenius, Kristina, Oakes, Nicholas D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259322/
https://ncbi.nlm.nih.gov/pubmed/25486018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113328
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