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Pharmacological PPARα Activation Markedly Alters Plasma Turnover of the Amino Acids Glycine, Serine and Arginine in the Rat
The current study extends previously reported PPARα agonist WY 14,643 (30 µmol/kg/day for 4 weeks) effects on circulating amino acid concentrations in rats fed a 48% saturated fat diet. Steady-state tracer experiments were used to examine in vivo kinetic mechanisms underlying altered plasma serine,...
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Publicado no: | PLoS One |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4259322/ https://ncbi.nlm.nih.gov/pubmed/25486018 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113328 |
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