WNT7b mediates macrophage-induced programmed cell death in patterning of the vasculature

Macrophages have a critical role in inflammatory and immune responses through their ability to recognize and engulf apoptotic cells(1). Here we show that macrophages initiate a cell-death programme in target cells by activating the canonical WNT pathway. We show in mice that macrophage WNT7b is a sh...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Lobov, Ivan B., Rao, Sujata, Carroll, Thomas J., Vallance, Jefferson E., Ito, Masataka, Ondr, Jennifer K., Kurup, Savita, Glass, Donald A., Patel, Millan S., Shu, Weiguo, Morrisey, Edward E., McMahon, Andrew P., Karsenty, Gerard, Lang, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259146/
https://ncbi.nlm.nih.gov/pubmed/16163358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature03928
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