miR-543 and miR-590-3p regulate human mesenchymal stem cell aging via direct targeting of AIMP3/p18

Previously, AIMP3 (aminoacyl-tRNAsynthetase-interacting multifunctional protein-3) was shown to be involved in the macromolecular tRNA synthetase complex or to act as a tumor suppressor. In this study, we report a novel role of AIMP3/p18 in the cellular aging of human mesenchymal stem cells (hMSCs)....

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Bibliographic Details
Published in:Age (Dordr)
Main Authors: Lee, Seunghee, Yu, Kyung-Rok, Ryu, Young-Sil, Oh, Young Sun, Hong, In-Sun, Kim, Hyung-Sik, Lee, Jin Young, Kim, Sunghoon, Seo, Kwang-Won, Kang, Kyung-Sun
Format: Artigo
Language:Inglês
Published: Springer Netherlands 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259092/
https://ncbi.nlm.nih.gov/pubmed/25465621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-014-9724-2
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