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Covalent Immobilization of Microtubules on Glass Surfaces for Molecular Motor Force Measurements and Other Single-Molecule Assays

Rigid attachment of microtubules (MTs) to glass cover slip surfaces is a prerequisite for a variety of microscopy experiments in which MTs are used as substrates for MT-associated proteins, such as the molecular motors kinesin and cytoplasmic dynein. We present an MT-surface coupling protocol in whi...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Nicholas, Matthew P., Rao, Lu, Gennerich, Arne
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258907/
https://ncbi.nlm.nih.gov/pubmed/24633798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-0329-0_9
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