IL-33 promotes ST2-dependent lung fibrosis by the induction of alternatively activated macrophages and innate lymphoid cells in mice

BACKGROUND: The initiation and regulation of pulmonary fibrosis are not well understood. IL-33, an important cytokine for respiratory diseases, is overexpressed in the lungs of patients with idiopathic pulmonary fibrosis. OBJECTIVES: We aimed to determine the effects and mechanism of IL-33 on the de...

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Vydáno v:J Allergy Clin Immunol
Hlavní autoři: Li, Dong, Guabiraba, Rodrigo, Besnard, Anne-Gaëlle, Komai-Koma, Mousa, Jabir, Majid S., Zhang, Li, Graham, Gerard J., Kurowska-Stolarska, Mariola, Liew, Foo Y., McSharry, Charles, Xu, Damo
Médium: Artigo
Jazyk:Inglês
Vydáno: Mosby 2014
Témata:
Mechanisms of Allergy and Clinical Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258609/
https://ncbi.nlm.nih.gov/pubmed/24985397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2014.05.011
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