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Paclitaxel-loaded PEG-PE-based micellar nanopreparations targeted with tumor specific landscape phage fusion protein enhance apoptosis and efficiently reduce tumors

In an effort to improve the therapeutic index of cancer chemotherapy, we developed an advanced nanopreparation based on the combination of landscape phage display to obtain new targeting ligands with micellar nanoparticles for tumor targeting of water insoluble neoplastic agents. With paclitaxel as...

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Publicat a:Mol Cancer Ther
Autors principals: Wang, Tao, Yang, Shenghong, Mei, Leslie A., Parmar, Chirag K., Gillespie, James W., Praveen, Kulkarni P., Petrenko, Valery A., Torchilin, Vladimir P.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258532/
https://ncbi.nlm.nih.gov/pubmed/25239936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0052
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