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Determining the Origins of Superoxide and Hydrogen Peroxide in the Mammalian NADH: Ubiquinone Oxidoreductase

NADH: ubiquinone oxidoreductase (Complex I) is a proton pump in the electron transport chain that can produce a significant amounts of superoxide and hydrogen peroxide. While the flavin mononucleotide (FMN) is the putative site for hydrogen peroxide generation, sites responsible for superoxide are l...

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Publicat a:Free Radic Biol Med
Autors principals: Bazil, Jason N., Pannala, Venkat R., Dash, Ranjan K., Beard, Daniel A.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258523/
https://ncbi.nlm.nih.gov/pubmed/25236739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.08.023
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