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FIH-1 Disrupts an LRRK1/EGFR Complex to Positively Regulate Keratinocyte Migration

Factor inhibiting hypoxia-inducible factor 1 (FIH-1; official symbol HIF1AN) is a hydroxylase that negatively regulates hypoxia-inducible factor 1α but also targets other ankyrin repeat domain–containing proteins such as Notch receptor to limit epithelial differentiation. We show that FIH-1 null mut...

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Foilsithe in:Am J Pathol
Main Authors: Peng, Han, Kaplan, Nihal, Yang, Wending, Getsios, Spiro, Lavker, Robert M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Investigative Pathology 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258497/
https://ncbi.nlm.nih.gov/pubmed/25455687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.08.014
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