Calmodulin antagonists induce cell cycle arrest and apoptosis in vitro and inhibit tumor growth in vivo in human multiple myeloma

BACKGROUND: Human multiple myeloma (MM) is an incurable hematological malignancy for which novel therapeutic agents are needed. Calmodulin (CaM) antagonists have been reported to induce apoptosis and inhibit tumor cell invasion and metastasis in various tumor models. However, the antitumor effects o...

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Publicado no:BMC Cancer
Main Authors: Yokokura, Shigeyuki, Yurimoto, Saki, Matsuoka, Akihito, Imataki, Osamu, Dobashi, Hiroaki, Bandoh, Shuji, Matsunaga, Takuya
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258255/
https://ncbi.nlm.nih.gov/pubmed/25424011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-882
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